The Amyloid-beta rich CNS environment alters myeloid cell functionality independent of their origin

Microglia, the innate immune cells of the central nervous system (CNS) survey their surroundings with their cytoplasmic processes, phagocytose debris and rapidly respond to injury. These functions are affected by the presence of beta-Amyloid (Aβ) deposits, hallmark lesions of Alzheimer’s disease (AD...

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Detalles Bibliográficos
Autores principales: Drost, Natalia, Houtman, Judith, Cseresnyés, Zoltán, Niesner, Raluca, Rinnenthal, Jan-Leo, Miller, Kelly R., Prokop, Stefan, Heppner, Frank L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189379/
https://www.ncbi.nlm.nih.gov/pubmed/32346002
http://dx.doi.org/10.1038/s41598-020-63989-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189379/
https://www.ncbi.nlm.nih.gov/pubmed/32346002
http://dx.doi.org/10.1038/s41598-020-63989-3

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