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Dynamics of a Key Conformational Transition in the Mechanism of Peroxiredoxin Sulfinylation
[Image: see text] Peroxiredoxins from the Prx1 subfamily (Prx) are moonlighting peroxidases that operate in peroxide signaling and are regulated by sulfinylation. Prxs offer a major model of protein–thiol oxidative modification. They react with H(2)O(2) to form a sulfenic acid intermediate that eith...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189429/ https://www.ncbi.nlm.nih.gov/pubmed/32363077 http://dx.doi.org/10.1021/acscatal.9b04471 |