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Microglia knockdown reduces inflammation and preserves cognition in diabetic animals after experimental stroke

INTRODUCTION: Unfortunately, over 40% of stroke victims have pre-existing diabetes which not only increases their risk of stroke up to 2–6 fold, but also worsens both functional recovery and the severity of cognitive impairment. Our lab has recently linked the chronic inflammation in diabetes to poo...

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Detalles Bibliográficos
Autores principales: Jackson, Ladonya, Dumanli, Selin, Johnson, Maribeth H., Fagan, Susan C., Ergul, Adviye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189436/
https://www.ncbi.nlm.nih.gov/pubmed/32345303
http://dx.doi.org/10.1186/s12974-020-01815-3