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Human CD8(+)CD28(−) T suppressor cells expanded by common gamma chain (γc) cytokines retain steady allospecific suppressive capacity in vivo
BACKGROUND: CD8(+)CD28(−) T suppressor (Ts) cells play critical role in transplant tolerance. Our previous study has generated CD8(+)CD28(−) Ts cells in vitro which exert robust allospecific suppressive capacity in vitro. RESULTS: CD8(+)CD28(−) Ts cells were expanded by stimulating human CD8(+) T ce...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189520/ https://www.ncbi.nlm.nih.gov/pubmed/32349664 http://dx.doi.org/10.1186/s12865-020-00354-z |