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Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues

BACKGROUND: Endogenous retroelements (EREs) constitute about 42% of the human genome and have been implicated in common human diseases such as autoimmunity and cancer. The dominant paradigm holds that EREs are expressed in embryonic stem cells (ESCs) and germline cells but are repressed in different...

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Detalles Bibliográficos
Autores principales: Larouche, Jean-David, Trofimov, Assya, Hesnard, Leslie, Ehx, Gregory, Zhao, Qingchuan, Vincent, Krystel, Durette, Chantal, Gendron, Patrick, Laverdure, Jean-Philippe, Bonneil, Éric, Côté, Caroline, Lemieux, Sébastien, Thibault, Pierre, Perreault, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189544/
https://www.ncbi.nlm.nih.gov/pubmed/32345368
http://dx.doi.org/10.1186/s13073-020-00740-7