Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor

BACKGROUND: Pancreatic neuroendocrine tumors (PANETs) are rare, slow growing cancers that often present with local and distant metastasis upon detection. PANETS contain distinct karyotypes, epigenetic dysregulation, and recurrent mutations in MEN1, ATRX, and DAXX (MAD+); however, the molecular basis...

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Detalles Bibliográficos
Autores principales: Quevedo, Rene, Spreafico, Anna, Bruce, Jeff, Danesh, Arnavaz, El Ghamrasni, Samah, Giesler, Amanda, Hanna, Youstina, Have, Cherry, Li, Tiantian, Yang, S. Y. Cindy, Zhang, Tong, Asa, Sylvia L., Haibe-Kains, Benjamin, Krzyzanowska, Monika, Smith, Adam C., Singh, Simron, Siu, Lillian L., Pugh, Trevor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189550/
https://www.ncbi.nlm.nih.gov/pubmed/32345369
http://dx.doi.org/10.1186/s13073-020-00730-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189550/
https://www.ncbi.nlm.nih.gov/pubmed/32345369
http://dx.doi.org/10.1186/s13073-020-00730-9

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