Cargando…

General Adaptation in Critical Illness: Glucocorticoid Receptor-alpha Master Regulator of Homeostatic Corrections

In critical illness, homeostatic corrections representing the culmination of hundreds of millions of years of evolution, are modulated by the activated glucocorticoid receptor alpha (GRα) and are associated with an enormous bioenergetic and metabolic cost. Appreciation of how homeostatic corrections...

Descripción completa

Detalles Bibliográficos
Autores principales: Meduri, Gianfranco Umberto, Chrousos, George P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189617/
https://www.ncbi.nlm.nih.gov/pubmed/32390938
http://dx.doi.org/10.3389/fendo.2020.00161