Estimation of the Mutagenic Potential of 8-Oxog in Nuclear Extracts of Mouse Cells Using the “Framed Mirror” Method

We propose an improved earlier described “mirror” method for detecting in cell nuclear extracts mutations that arise in DNA during its replication due to the misincorporation of deoxyadenosine-5′-monophosphate (dAMP) opposite 7,8-dihydro-8-oxoguanine (8-oxoG). This method is based on the synthesis o...

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Detalles Bibliográficos
Autores principales: Gening, Leonid V., Volodin, Alexandr A., Kazachenko, Konstantin Y., Makarova, Irina V., Tarantul, Vyacheslav Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189664/
https://www.ncbi.nlm.nih.gov/pubmed/31947764
http://dx.doi.org/10.3390/mps3010003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189664/
https://www.ncbi.nlm.nih.gov/pubmed/31947764
http://dx.doi.org/10.3390/mps3010003

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