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Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples
BACKGROUND: Large numbers of autosomal sites are found differentially methylated in the aging genome. Due to analytical difficulties in dealing with sex differences in X-chromosome content and X-inactivation (XCI) in females, this has not been explored for the X chromosome. METHODS: Using data from...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189689/ https://www.ncbi.nlm.nih.gov/pubmed/32345361 http://dx.doi.org/10.1186/s13073-020-00736-3 |