Cargando…

Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

BACKGROUND: Large numbers of autosomal sites are found differentially methylated in the aging genome. Due to analytical difficulties in dealing with sex differences in X-chromosome content and X-inactivation (XCI) in females, this has not been explored for the X chromosome. METHODS: Using data from...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Shuxia, Lund, Jesper B., Christensen, Kaare, Baumbach, Jan, Mengel-From, Jonas, Kruse, Torben, Li, Weilong, Mohammadnejad, Afsaneh, Pattie, Alison, Marioni, Riccardo E., Deary, Ian J., Tan, Qihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189689/ https://www.ncbi.nlm.nih.gov/pubmed/32345361 http://dx.doi.org/10.1186/s13073-020-00736-3

Ejemplares similares

Age‐dependent DNA methylation patterns on the Y chromosome in elderly males
por: Lund, Jesper B., et al.
Publicado: (2019)

Novel DNA methylation marker discovery by assumption‐free genome‐wide association analysis of cognitive function in twins
por: Mohammadnejad, Afsaneh, et al.
Publicado: (2021)

Global Gene Expression Profiling and Transcription Factor Network Analysis of Cognitive Aging in Monozygotic Twins
por: Mohammadnejad, Afsaneh, et al.
Publicado: (2021)

Genetic and environmental determinants of O(6)-methylguanine DNA-methyltransferase (MGMT) gene methylation: a 10-year longitudinal study of Danish twins
por: Wang, Lijie, et al.
Publicado: (2021)

Generalized correlation coefficient for genome-wide association analysis of cognitive ability in twins
por: Mohammadnejad, Afsaneh, et al.
Publicado: (2020)

Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength
por: Soerensen, Mette, et al.
Publicado: (2019)

Age patterns of intra‐pair DNA methylation discordance in twins: Sex difference in epigenomic instability and implication on survival
por: Tan, Qihua, et al.
Publicado: (2021)

Sex difference in epigenomic instability during human aging
por: Tan, Qihua, et al.
Publicado: (2022)

Identification, replication and characterization of epigenetic remodelling in the aging genome: a cross population analysis
por: Li, Shuxia, et al.
Publicado: (2017)

DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns
por: Lund, Jesper Beltoft, et al.
Publicado: (2019)

A Genome-Wide Integrative Study of DNA Methylation, Gene Expression, and Later Life Hand Grip Strength
por: Soerensen, Mette, et al.
Publicado: (2020)

Skewness of X-chromosome inactivation increases with age and varies across birth cohorts in elderly Danish women
por: Mengel-From, Jonas, et al.
Publicado: (2021)

Network based analysis of microarray gene expression profiles in response to electroacupuncture
por: Mohammadnejad, Afsaneh, et al.
Publicado: (2019)

Retrospective analysis of main and interaction effects in genetic association studies of human complex traits
por: Tan, Qihua, et al.
Publicado: (2007)

Power Estimation for Gene-Longevity Association Analysis Using Concordant Twins
por: Tan, Qihua, et al.
Publicado: (2014)

CLU Genetic Variants and Cognitive Decline among Elderly and Oldest Old
por: Mengel-From, Jonas, et al.
Publicado: (2013)

Heritability and circulating concentrations of pregnancy-associated plasma protein-A and stanniocalcin-2 in elderly monozygotic and dizygotic twins
por: Hjortebjerg, Rikke, et al.
Publicado: (2023)

Genetic Variants Correlate With Better Processing Speed
por: Gurinovich, Anastasia, et al.
Publicado: (2021)

Sex and age specific reduction in stress resistance and mitochondrial DNA copy number in Drosophila melanogaster
por: Kristensen, Torsten Nygaard, et al.
Publicado: (2019)

Longitudinal changes in the genetic and environmental influences on the epigenetic clocks across old age: Evidence from two twin cohorts
por: Jylhävä, Juulia, et al.
Publicado: (2019)

A Combinatory Approach for Selecting Prognostic Genes in Microarray Studies of Tumour Survivals
por: Tan, Qihua, et al.
Publicado: (2009)

Epigenome-wide association study of leukocyte telomere length
por: Lee, Yunsung, et al.
Publicado: (2019)

Epigenetic signature of preterm birth in adult twins
por: Tan, Qihua, et al.
Publicado: (2018)

Differential DNA methylation patterns of polycystic ovarian syndrome in whole blood of Chinese women
por: Li, Shuxia, et al.
Publicado: (2016)

DNA Methylation and All-Cause Mortality in Middle-Aged and Elderly Danish Twins
por: Svane, Anne Marie, et al.
Publicado: (2018)

Hierarchical linear modeling of longitudinal pedigree data for genetic association analysis
por: Tan, Qihua, et al.
Publicado: (2014)

Genetic and Environmental Regulation on Longitudinal Change of Metabolic Phenotypes in Danish and Chinese Adult Twins
por: Li, Shuxia, et al.
Publicado: (2016)

Longitudinal Investigation into Genetics in the Conservation of Metabolic Phenotypes in Danish and Chinese Twins
por: Li, Shuxia, et al.
Publicado: (2016)

A Growth Curve Model with Fractional Polynomials for Analysing Incomplete Time-Course Data in Microarray Gene Expression Studies
por: Tan, Qihua, et al.
Publicado: (2011)

Genome-wide DNA methylation and gene expression analyses in monozygotic twins identify potential biomarkers of depression
por: Wang, Weijing, et al.
Publicado: (2021)

Efficient Sample Tracking With OpenLabFramework
por: List, Markus, et al.
Publicado: (2014)

Genetic determinants of hair and eye colours in the Scottish and Danish populations
por: Mengel-From, Jonas, et al.
Publicado: (2009)

Patients with osteoarthritis are least likely to receive lifestyle advice compared with patients with diabetes and hypertension: A national health survey study from Denmark
por: Baumbach, Linda, et al.
Publicado: (2020)

Gene expression meta-analysis identifies metastatic pathways and transcription factors in breast cancer
por: Thomassen, Mads, et al.
Publicado: (2008)

Feature Selection for Predicting Tumor Metastases in Microarray Experiments using Paired Design
por: Tan, Qihua, et al.
Publicado: (2007)

Sampling rate dependence of correlation at long time lags in BOLD fMRI measurements on humans and gel phantoms
por: Mikkelsen, Kaare B., et al.
Publicado: (2013)

DNA methylation QTL analysis identifies new regulators of human longevity
por: Szymczak, Silke, et al.
Publicado: (2020)

Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921
por: Harris, Sarah E., et al.
Publicado: (2016)

Epigenome-wide association study in Chinese monozygotic twins identifies DNA methylation loci associated with blood pressure
por: Wang, Weijing, et al.
Publicado: (2023)

Lower levels of FOXP3 are associated with prolonged inflammatory responses in kidney transplant recipients
por: Saleh, Qais W., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_72249st7g6do5h5p4ei60qimld