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Origin of the nuclear proteome on the basis of pre-existing nuclear localization signals in prokaryotic proteins

BACKGROUND: The origin of the selective nuclear protein import machinery, which consists of nuclear pore complexes and adaptor molecules interacting with the nuclear localization signals (NLSs) of cargo molecules, is one of the most important events in the evolution of eukaryotic cells. How proteins...

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Detalles Bibliográficos
Autores principales: Lisitsyna, Olga M., Kurnaeva, Margarita A., Arifulin, Eugene A., Shubina, Maria Y., Musinova, Yana R., Mironov, Andrey A., Sheval, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189692/
https://www.ncbi.nlm.nih.gov/pubmed/32345340
http://dx.doi.org/10.1186/s13062-020-00263-6