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Natural presence of the V179D and K103R/V179D mutations associated with resistance to nonnucleoside reverse transcriptase inhibitors in HIV-1 CRF65_cpx strains

BACKGROUND: There is increasing evidence that HIV-1 genetic diversity can have an impact on drug resistance. The aim of this study is to investigate the epidemiological situation of CRF65_cpx and the impact of natural polymorphisms of this variant on genotypic resistance. METHODS: We used the BLAST...

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Detalles Bibliográficos
Autores principales: Liu, Yongjian, Zhang, Yu, Li, Hanping, Wang, Xiaolin, Jia, Lei, Han, Jingwan, Li, Tianyi, Li, Jingyun, Li, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189696/
https://www.ncbi.nlm.nih.gov/pubmed/32345262
http://dx.doi.org/10.1186/s12879-020-05007-5