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M2 Macrophagy-derived exosomal miRNA-5106 induces bone mesenchymal stem cells towards osteoblastic fate by targeting salt-inducible kinase 2 and 3

BACKGROUND: Osteoblast differentiation is a vital process for fracture healing, and exosomes are nanosized membrane vesicles that can deliver therapeutic drugs easily and safely. Macrophages participate in the regulation of various biological processes in vivo, and macrophage-derived exosomes (MD-Ex...

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Detalles Bibliográficos
Autores principales: Xiong, Yuan, Chen, Lang, Yan, Chenchen, Zhou, Wu, Yu, Tao, Sun, Yun, Cao, Faqi, Xue, Hang, Hu, Yiqiang, Chen, Dong, Mi, Bobin, Liu, Guohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189726/
https://www.ncbi.nlm.nih.gov/pubmed/32345321
http://dx.doi.org/10.1186/s12951-020-00622-5