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miR‐155‐5p inhibition rejuvenates aged mesenchymal stem cells and enhances cardioprotection following infarction

Aging impairs the functions of human mesenchymal stem cells (MSCs), thereby severely reducing their beneficial effects on myocardial infarction (MI). MicroRNAs (miRNAs) play crucial roles in regulating the senescence of MSCs; however, the underlying mechanisms remain unclear. Here, we investigated t...

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Detalles Bibliográficos
Autores principales: Hong, Yimei, He, Haiwei, Jiang, Guojun, Zhang, Hao, Tao, Wuyuan, Ding, Yue, Yuan, Dongsheng, Liu, Jing, Fan, Huimin, Lin, Fang, Liang, Xiaoting, Li, Xin, Zhang, Yuelin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189985/
https://www.ncbi.nlm.nih.gov/pubmed/32196916
http://dx.doi.org/10.1111/acel.13128