Cargando…
miR‐155‐5p inhibition rejuvenates aged mesenchymal stem cells and enhances cardioprotection following infarction
Aging impairs the functions of human mesenchymal stem cells (MSCs), thereby severely reducing their beneficial effects on myocardial infarction (MI). MicroRNAs (miRNAs) play crucial roles in regulating the senescence of MSCs; however, the underlying mechanisms remain unclear. Here, we investigated t...
Autores principales: | Hong, Yimei, He, Haiwei, Jiang, Guojun, Zhang, Hao, Tao, Wuyuan, Ding, Yue, Yuan, Dongsheng, Liu, Jing, Fan, Huimin, Lin, Fang, Liang, Xiaoting, Li, Xin, Zhang, Yuelin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189985/ https://www.ncbi.nlm.nih.gov/pubmed/32196916 http://dx.doi.org/10.1111/acel.13128 |
Ejemplares similares
-
Apelin Rejuvenates Aged Human Mesenchymal Stem Cells by Regulating Autophagy and Improves Cardiac Protection After Infarction
por: Zhang, Hao, et al.
Publicado: (2021) -
Macrophage migration inhibitory factor rejuvenates aged human mesenchymal stem cells and improves myocardial repair
por: Zhang, Yuelin, et al.
Publicado: (2019) -
Adipose-Derived Mesenchymal Stem Cells Isolated from Patients with Abdominal Aortic Aneurysm Exhibit Senescence Phenomena
por: Huang, Xiaoran, et al.
Publicado: (2019) -
Apelin-13 Pretreatment Promotes the Cardioprotective Effect of Mesenchymal Stem Cells against Myocardial Infarction by Improving Their Survival
por: Chen, Guona, et al.
Publicado: (2022) -
Inhibition of miR-199a-5p rejuvenates aged mesenchymal stem cells derived from patients with idiopathic pulmonary fibrosis and improves their therapeutic efficacy in experimental pulmonary fibrosis
por: Shi, Linli, et al.
Publicado: (2021)