Galactose‐modified duocarmycin prodrugs as senolytics

Senescence is a stable growth arrest that impairs the replication of damaged, old or preneoplastic cells, therefore contributing to tissue homeostasis. Senescent cells accumulate during ageing and are associated with cancer, fibrosis and many age‐related pathologies. Recent evidence suggests that th...

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Detalles Bibliográficos
Autores principales: Guerrero, Ana, Guiho, Romain, Herranz, Nicolás, Uren, Anthony, Withers, Dominic J., Martínez‐Barbera, Juan Pedro, Tietze, Lutz F., Gil, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189988/
https://www.ncbi.nlm.nih.gov/pubmed/32175667
http://dx.doi.org/10.1111/acel.13133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189988/
https://www.ncbi.nlm.nih.gov/pubmed/32175667
http://dx.doi.org/10.1111/acel.13133

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