Inhibition of histone acetyltransferase GCN5 extends lifespan in both yeast and human cell lines

Histone acetyltransferases (HATs) are important enzymes that transfer acetyl groups onto histones and thereby regulate both gene expression and chromosomal structures. Previous work has shown that the activation of sirtuins, which are histone deacetylases, can extend lifespan. This suggests that inh...

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Detalles Bibliográficos
Autores principales: Huang, Boyue, Zhong, Dandan, Zhu, Jie, An, Yongpan, Gao, Miaomiao, Zhu, Shuai, Dang, Weiwei, Wang, Xin, Yang, Baoxue, Xie, Zhengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189995/
https://www.ncbi.nlm.nih.gov/pubmed/32157780
http://dx.doi.org/10.1111/acel.13129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189995/
https://www.ncbi.nlm.nih.gov/pubmed/32157780
http://dx.doi.org/10.1111/acel.13129

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