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Age attenuates the T‐type Ca(V)3.2‐RyR axis in vascular smooth muscle

Caveolae position Ca(V)3.2 (T‐type Ca(2+) channel encoded by the α‐3.2 subunit) sufficiently close to RyR (ryanodine receptors) for extracellular Ca(2+) influx to trigger Ca(2+) sparks and large‐conductance Ca(2+)‐activated K(+) channel feedback in vascular smooth muscle. We hypothesize that this me...

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Detalles Bibliográficos
Autores principales: Fan, Gang, Kaßmann, Mario, Cui, Yingqiu, Matthaeus, Claudia, Kunz, Séverine, Zhong, Cheng, Zhu, Shuai, Xie, Yu, Tsvetkov, Dmitry, Daumke, Oliver, Huang, Yu, Gollasch, Maik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189999/
https://www.ncbi.nlm.nih.gov/pubmed/32187825
http://dx.doi.org/10.1111/acel.13134