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Relaxed constraint and functional divergence of the progesterone receptor (PGR) in the human stem-lineage

The steroid hormone progesterone, acting through the progesterone receptor (PR), a ligand-activated DNA-binding transcription factor, plays an essential role in regulating nearly every aspect of female reproductive biology. While many reproductive traits regulated by PR are conserved in mammals, Cat...

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Detalles Bibliográficos
Autores principales: Marinić, Mirna, Lynch, Vincent J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190170/
https://www.ncbi.nlm.nih.gov/pubmed/32302297
http://dx.doi.org/10.1371/journal.pgen.1008666