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Relaxed constraint and functional divergence of the progesterone receptor (PGR) in the human stem-lineage
The steroid hormone progesterone, acting through the progesterone receptor (PR), a ligand-activated DNA-binding transcription factor, plays an essential role in regulating nearly every aspect of female reproductive biology. While many reproductive traits regulated by PR are conserved in mammals, Cat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190170/ https://www.ncbi.nlm.nih.gov/pubmed/32302297 http://dx.doi.org/10.1371/journal.pgen.1008666 |