Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis

Giardiasis and other protozoan infections are major worldwide causes of morbidity and mortality, yet development of new antimicrobial agents with improved efficacy and ability to override increasingly common drug resistance remains a major challenge. Antimicrobial drug development typically proceeds...

Descripción completa

Detalles Bibliográficos
Autores principales: Lauwaet, Tineke, Miyamoto, Yukiko, Ihara, Sozaburo, Le, Christine, Kalisiak, Jarosław, Korthals, Keith A., Ghassemian, Majid, Smith, Diane K., Sharpless, K. Barry, Fokin, Valery V., Eckmann, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190177/
https://www.ncbi.nlm.nih.gov/pubmed/32302296
http://dx.doi.org/10.1371/journal.pntd.0008224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190177/
https://www.ncbi.nlm.nih.gov/pubmed/32302296
http://dx.doi.org/10.1371/journal.pntd.0008224

Ejemplares similares