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IL-36 signaling in keratinocytes controls early IL-23 production in psoriasis-like dermatitis

IL-36R signaling plays an important role in the pathogenesis of psoriasis. We ought to assess the specific function of IL-36R in keratinocytes for the pathology of Aldara-induced psoriasis-like dermatitis. Il36r(ΔK) mice presenting deletion of IL-36R in keratinocytes were similarly resistant to Alda...

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Detalles Bibliográficos
Autores principales: Goldstein, Jérémie D, Bassoy, Esen Y, Caruso, Assunta, Palomo, Jennifer, Rodriguez, Emiliana, Lemeille, Sylvain, Gabay, Cem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190273/
https://www.ncbi.nlm.nih.gov/pubmed/32345660
http://dx.doi.org/10.26508/lsa.202000688