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Immunoglobulin expression in the endoplasmic reticulum shapes the metabolic fitness of B lymphocytes

The major function of B lymphocytes is to sense antigens and to produce protective antibodies after activation. This function requires the expression of a B-cell antigen receptor (BCR), and evolutionary conserved mechanisms seem to exist that ensure that B cells without a BCR do not develop nor surv...

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Detalles Bibliográficos
Autores principales: Jumaa, Huda, Caganova, Marieta, McAllister, Ellen J, Hoenig, Laura, He, Xiaocui, Saltukoglu, Deniz, Brenker, Kathrin, Köhler, Markus, Leben, Ruth, Hauser, Anja E, Niesner, Raluca, Rajewsky, Klaus, Reth, Michael, Jellusova, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190274/
https://www.ncbi.nlm.nih.gov/pubmed/32341085
http://dx.doi.org/10.26508/lsa.202000700