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Immunoglobulin expression in the endoplasmic reticulum shapes the metabolic fitness of B lymphocytes
The major function of B lymphocytes is to sense antigens and to produce protective antibodies after activation. This function requires the expression of a B-cell antigen receptor (BCR), and evolutionary conserved mechanisms seem to exist that ensure that B cells without a BCR do not develop nor surv...
Autores principales: | Jumaa, Huda, Caganova, Marieta, McAllister, Ellen J, Hoenig, Laura, He, Xiaocui, Saltukoglu, Deniz, Brenker, Kathrin, Köhler, Markus, Leben, Ruth, Hauser, Anja E, Niesner, Raluca, Rajewsky, Klaus, Reth, Michael, Jellusova, Julia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190274/ https://www.ncbi.nlm.nih.gov/pubmed/32341085 http://dx.doi.org/10.26508/lsa.202000700 |
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