Paneth cell α-defensin misfolding correlates with dysbiosis and ileitis in Crohn’s disease model mice

Crohn’s disease (CD) is an intractable inflammatory bowel disease, and dysbiosis, disruption of the intestinal microbiota, is associated with CD pathophysiology. ER stress, disruption of ER homeostasis in Paneth cells of the small intestine, and α-defensin misfolding have been reported in CD patient...

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Detalles Bibliográficos
Autores principales: Shimizu, Yu, Nakamura, Kiminori, Yoshii, Aki, Yokoi, Yuki, Kikuchi, Mani, Shinozaki, Ryuga, Nakamura, Shunta, Ohira, Shuya, Sugimoto, Rina, Ayabe, Tokiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190275/
https://www.ncbi.nlm.nih.gov/pubmed/32345659
http://dx.doi.org/10.26508/lsa.201900592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190275/
https://www.ncbi.nlm.nih.gov/pubmed/32345659
http://dx.doi.org/10.26508/lsa.201900592

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