Mathematical prediction of clinical outcomes in advanced cancer patients treated with checkpoint inhibitor immunotherapy

We present a mechanistic mathematical model of immune checkpoint inhibitor therapy to address the oncological need for early, broadly applicable readouts (biomarkers) of patient response to immunotherapy. The model is built upon the complex biological and physical interactions between the immune sys...

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Detalles Bibliográficos
Autores principales: Butner, Joseph D., Elganainy, Dalia, Wang, Charles X., Wang, Zhihui, Chen, Shu-Hsia, Esnaola, Nestor F., Pasqualini, Renata, Arap, Wadih, Hong, David S., Welsh, James, Koay, Eugene J., Cristini, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190324/
https://www.ncbi.nlm.nih.gov/pubmed/32426472
http://dx.doi.org/10.1126/sciadv.aay6298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190324/
https://www.ncbi.nlm.nih.gov/pubmed/32426472
http://dx.doi.org/10.1126/sciadv.aay6298

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