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Lineage hierarchies and stochasticity ensure the long-term maintenance of adult neural stem cells

The cellular basis and extent of neural stem cell (NSC) self-renewal in adult vertebrates, and their heterogeneity, remain controversial. To explore the functional behavior and dynamics of individual NSCs, we combined genetic lineage tracing, quantitative clonal analysis, intravital imaging, and glo...

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Detalles Bibliográficos
Autores principales: Than-Trong, Emmanuel, Kiani, Bahareh, Dray, Nicolas, Ortica, Sara, Simons, Benjamin, Rulands, Steffen, Alunni, Alessandro, Bally-Cuif, Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190328/
https://www.ncbi.nlm.nih.gov/pubmed/32426477
http://dx.doi.org/10.1126/sciadv.aaz5424