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Lineage hierarchies and stochasticity ensure the long-term maintenance of adult neural stem cells
The cellular basis and extent of neural stem cell (NSC) self-renewal in adult vertebrates, and their heterogeneity, remain controversial. To explore the functional behavior and dynamics of individual NSCs, we combined genetic lineage tracing, quantitative clonal analysis, intravital imaging, and glo...
Autores principales: | Than-Trong, Emmanuel, Kiani, Bahareh, Dray, Nicolas, Ortica, Sara, Simons, Benjamin, Rulands, Steffen, Alunni, Alessandro, Bally-Cuif, Laure |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190328/ https://www.ncbi.nlm.nih.gov/pubmed/32426477 http://dx.doi.org/10.1126/sciadv.aaz5424 |
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