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Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation

Glaucoma is a group of progressive optic neuropathies that cause irreversible vision loss. Although elevated intraocular pressure (IOP) is associated with the development and progression of glaucoma, the mechanisms for its regulation are not well understood. Here, we have designed CIBN/CRY2-based op...

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Detalles Bibliográficos
Autores principales: Prosseda, Philipp P., Alvarado, Jorge A., Wang, Biao, Kowal, Tia J., Ning, Ke, Stamer, W. Daniel, Hu, Yang, Sun, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190330/
https://www.ncbi.nlm.nih.gov/pubmed/32494665
http://dx.doi.org/10.1126/sciadv.aay8699