Cargando…
Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation
Glaucoma is a group of progressive optic neuropathies that cause irreversible vision loss. Although elevated intraocular pressure (IOP) is associated with the development and progression of glaucoma, the mechanisms for its regulation are not well understood. Here, we have designed CIBN/CRY2-based op...
Autores principales: | Prosseda, Philipp P., Alvarado, Jorge A., Wang, Biao, Kowal, Tia J., Ning, Ke, Stamer, W. Daniel, Hu, Yang, Sun, Yang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190330/ https://www.ncbi.nlm.nih.gov/pubmed/32494665 http://dx.doi.org/10.1126/sciadv.aay8699 |
Ejemplares similares
-
Optogenetic Modulation of Intraocular Pressure in a Glucocorticoid-Induced Ocular Hypertension Mouse Model
por: Kowal, Tia J., et al.
Publicado: (2021) -
Advances in Ophthalmic Optogenetics: Approaches and Applications
por: Prosseda, Philipp P., et al.
Publicado: (2022) -
Primary Cilia in Amacrine Cells in Retinal Development
por: Ning, Ke, et al.
Publicado: (2021) -
Phosphoinositide lipids in primary cilia biology
por: Conduit, Sarah E., et al.
Publicado: (2020) -
INPP5E regulates phosphoinositide-dependent cilia transition zone function
por: Dyson, Jennifer M., et al.
Publicado: (2017)