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Structural monitoring of a transient intermediate in the hemagglutinin fusion machinery on influenza virions
The influenza virus hemagglutinin (HA) fusion protein has long been viewed as a “spring-loaded” fusion machine whereby activation at low pH initiates a rapid and irreversible cascade of conformational changes that drives the membrane fusion reaction. This mechanism has shaped our understanding of ho...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190341/ https://www.ncbi.nlm.nih.gov/pubmed/32494683 http://dx.doi.org/10.1126/sciadv.aaz8822 |