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IgG(3) (+) B cells are associated with the development of multiple sclerosis

OBJECTIVES: Disease‐modifying therapies (DMTs) targeting B cells are amongst the most effective for preventing multiple sclerosis (MS) progression. IgG(3) antibodies and their uncharacterised B‐cell clones are predicted to play a pathogenic role in MS. Identifying subsets of IgG(3) (+) B cells invol...

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Detalles Bibliográficos
Autores principales: Marsh‐Wakefield, Felix, Ashhurst, Thomas, Trend, Stephanie, McGuire, Helen M, Juillard, Pierre, Zinger, Anna, Jones, Anderson P, Kermode, Allan G, Hawke, Simon, Grau, Georges E, Hart, Prue H, Byrne, Scott N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190396/
https://www.ncbi.nlm.nih.gov/pubmed/32355561
http://dx.doi.org/10.1002/cti2.1133