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Lipogenic signalling modulates prostate cancer cell adhesion and migration via modification of Rho GTPases
Fatty acid synthase (FASN) is commonly overexpressed in prostate cancer and associated with tumour progression. FASN is responsible for de novo synthesis of the fatty acid palmitate; the building block for protein palmitoylation. Recent work has suggested that alongside its established role in promo...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190568/ https://www.ncbi.nlm.nih.gov/pubmed/32139877 http://dx.doi.org/10.1038/s41388-020-1243-2 |