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Lipogenic signalling modulates prostate cancer cell adhesion and migration via modification of Rho GTPases

Fatty acid synthase (FASN) is commonly overexpressed in prostate cancer and associated with tumour progression. FASN is responsible for de novo synthesis of the fatty acid palmitate; the building block for protein palmitoylation. Recent work has suggested that alongside its established role in promo...

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Detalles Bibliográficos
Autores principales: De Piano, Mario, Manuelli, Valeria, Zadra, Giorgia, Otte, Jonathan, Edqvist, Per-Henrik D., Pontén, Fredrik, Nowinski, Salpie, Niaouris, Athanasios, Grigoriadis, Anita, Loda, Massimo, Van Hemelrijck, Mieke, Wells, Claire M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190568/
https://www.ncbi.nlm.nih.gov/pubmed/32139877
http://dx.doi.org/10.1038/s41388-020-1243-2