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Vimentin prevents a miR-dependent negative regulation of tissue factor mRNA during epithelial–mesenchymal transitions and facilitates early metastasis

Epithelial–mesenchymal transitions (EMTs) are high-profile in the field of circulating tumor cells (CTCs). EMT-shifted CTCs are considered to encompass pre-metastatic subpopulations though underlying molecular mechanisms remain elusive. Our previous work identified tissue factor (TF) as an EMT-induc...

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Detalles Bibliográficos
Autores principales: Francart, Marie-Emilie, Vanwynsberghe, Aline M., Lambert, Justine, Bourcy, Morgane, Genna, Anthony, Ancel, Julien, Perez-Boza, Jennifer, Noël, Agnès, Birembaut, Philippe, Struman, Ingrid, Polette, Myriam, Gilles, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190572/
https://www.ncbi.nlm.nih.gov/pubmed/32152404
http://dx.doi.org/10.1038/s41388-020-1244-1