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N-glycosylation of α(1D)-adrenergic receptor N-terminal domain is required for correct trafficking, function, and biogenesis

G protein-coupled receptor (GPCR) biogenesis, trafficking, and function are regulated by post-translational modifications, including N-glycosylation of asparagine residues. α(1D)-adrenergic receptors (α(1D)-ARs) – key regulators of central and autonomic nervous system function – contain two putative...

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Detalles Bibliográficos
Autores principales: Janezic, Eric M., Lauer, Sophia My-Linh, Williams, Robert George, Chungyoun, Michael, Lee, Kyung-Soon, Navaluna, Edelmar, Lau, Ho-Tak, Ong, Shao-En, Hague, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190626/
https://www.ncbi.nlm.nih.gov/pubmed/32350295
http://dx.doi.org/10.1038/s41598-020-64102-4