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N-glycosylation of α(1D)-adrenergic receptor N-terminal domain is required for correct trafficking, function, and biogenesis
G protein-coupled receptor (GPCR) biogenesis, trafficking, and function are regulated by post-translational modifications, including N-glycosylation of asparagine residues. α(1D)-adrenergic receptors (α(1D)-ARs) – key regulators of central and autonomic nervous system function – contain two putative...
Autores principales: | Janezic, Eric M., Lauer, Sophia My-Linh, Williams, Robert George, Chungyoun, Michael, Lee, Kyung-Soon, Navaluna, Edelmar, Lau, Ho-Tak, Ong, Shao-En, Hague, Chris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190626/ https://www.ncbi.nlm.nih.gov/pubmed/32350295 http://dx.doi.org/10.1038/s41598-020-64102-4 |
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