MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity

Besides pro-inflammatory roles, the ancient cytokine interleukin-17 (IL-17) modulates neural circuit function. We investigate IL-17 signaling in neurons, and the extent it can alter organismal phenotypes. We combine immunoprecipitation and mass spectrometry to biochemically characterize endogenous s...

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Detalles Bibliográficos
Autores principales: Flynn, Sean M., Chen, Changchun, Artan, Murat, Barratt, Stephen, Crisp, Alastair, Nelson, Geoffrey M., Peak-Chew, Sew-Yeu, Begum, Farida, Skehel, Mark, de Bono, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190641/
https://www.ncbi.nlm.nih.gov/pubmed/32350248
http://dx.doi.org/10.1038/s41467-020-15872-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190641/
https://www.ncbi.nlm.nih.gov/pubmed/32350248
http://dx.doi.org/10.1038/s41467-020-15872-y

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