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A live cell reporter of exosome secretion and uptake reveals pathfinding behavior of migrating cells

Small extracellular vesicles called exosomes affect multiple autocrine and paracrine cellular phenotypes. Understanding the function of exosomes requires a variety of tools, including live imaging. Our previous live-cell reporter, pHluorin-CD63, allows dynamic subcellular monitoring of exosome secre...

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Detalles Bibliográficos
Autores principales: Sung, Bong Hwan, von Lersner, Ariana, Guerrero, Jorge, Krystofiak, Evan S., Inman, David, Pelletier, Roxanne, Zijlstra, Andries, Ponik, Suzanne M., Weaver, Alissa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190671/
https://www.ncbi.nlm.nih.gov/pubmed/32350252
http://dx.doi.org/10.1038/s41467-020-15747-2