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Cyclic tensile strain facilitates ossification of the cervical posterior longitudinal ligament via increased Indian hedgehog signaling

The pathomechanisms of initiation and progression of ossification of the posterior longitudinal ligament (OPLL) are unclear. Indian hedgehog (Ihh) and related signaling molecules are key factors in normal enchondral ossification. The purpose of this study is to investigate the contribution of mechan...

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Detalles Bibliográficos
Autores principales: Sugita, Daisuke, Nakajima, Hideaki, Kokubo, Yasuo, Takeura, Naoto, Yayama, Takafumi, Matsumine, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190672/
https://www.ncbi.nlm.nih.gov/pubmed/32350355
http://dx.doi.org/10.1038/s41598-020-64304-w