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A Self-Assembling Lipidic Peptide and Selective Partial V2 Receptor Agonist Inhibits Urine Production

Lipidised analgesic peptide prodrugs self-assemble into peptide nanofibers; with the nanofiber morphology protecting the peptide from plasma degradation and improving therapeutic efficacy. Extending this learning, we hypothesised that a self-assembling lipidized peptide arginine vasopressin (AVP) re...

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Detalles Bibliográficos
Autores principales: Patel, Sunish, Volpe, Antonella Bavuso, Awwad, Sahar, Schätzlein, Andreas G., Haider, Shozeb, Liu, Boqian, Uchegbu, Ijeoma F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190706/
https://www.ncbi.nlm.nih.gov/pubmed/32350300
http://dx.doi.org/10.1038/s41598-020-64070-9