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Brain distribution of geissoschizine methyl ether in rats using mass spectrometry imaging analysis

Geissoschizine methyl ether (GM) is one of the main active ingredients responsible for ameliorating the behavioral and psychological symptoms of dementia (BPSD) in Kampo medicine yokukansan. GM is mainly metabolized into hydroxylated forms (HM-1/2). However, the brain distributions of GM and HM has...

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Detalles Bibliográficos
Autores principales: Matsumoto, Takashi, Ikarashi, Yasushi, Takiyama, Mikina, Watanabe, Junko, Setou, Mitsutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190722/
https://www.ncbi.nlm.nih.gov/pubmed/32350314
http://dx.doi.org/10.1038/s41598-020-63474-x