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Brain distribution of geissoschizine methyl ether in rats using mass spectrometry imaging analysis
Geissoschizine methyl ether (GM) is one of the main active ingredients responsible for ameliorating the behavioral and psychological symptoms of dementia (BPSD) in Kampo medicine yokukansan. GM is mainly metabolized into hydroxylated forms (HM-1/2). However, the brain distributions of GM and HM has...
Autores principales: | Matsumoto, Takashi, Ikarashi, Yasushi, Takiyama, Mikina, Watanabe, Junko, Setou, Mitsutoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190722/ https://www.ncbi.nlm.nih.gov/pubmed/32350314 http://dx.doi.org/10.1038/s41598-020-63474-x |
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