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ER Stress Regulates Immunosuppressive Function of Myeloid Derived Suppressor Cells in Leprosy that Can Be Overcome in the Presence of IFN-γ

Myeloid derived suppressor cells (MDSCs) are a population of immature myeloid cells that suppress adaptive immune function, yet the factors that regulate their suppressive function in patients with infection remain unclear. We studied MDSCs in patients with leprosy, a disease caused by Mycobacterium...

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Detalles Bibliográficos
Autores principales: Kelly-Scumpia, Kindra M., Choi, Aaron, Shirazi, Roksana, Bersabe, Hannah, Park, Esther, Scumpia, Philip O., Ochoa, Maria T., Yu, Jing, Ma, Feiyang, Pellegrini, Matteo, Modlin, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190750/
https://www.ncbi.nlm.nih.gov/pubmed/32339990
http://dx.doi.org/10.1016/j.isci.2020.101050