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ER Stress Regulates Immunosuppressive Function of Myeloid Derived Suppressor Cells in Leprosy that Can Be Overcome in the Presence of IFN-γ
Myeloid derived suppressor cells (MDSCs) are a population of immature myeloid cells that suppress adaptive immune function, yet the factors that regulate their suppressive function in patients with infection remain unclear. We studied MDSCs in patients with leprosy, a disease caused by Mycobacterium...
Autores principales: | Kelly-Scumpia, Kindra M., Choi, Aaron, Shirazi, Roksana, Bersabe, Hannah, Park, Esther, Scumpia, Philip O., Ochoa, Maria T., Yu, Jing, Ma, Feiyang, Pellegrini, Matteo, Modlin, Robert L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190750/ https://www.ncbi.nlm.nih.gov/pubmed/32339990 http://dx.doi.org/10.1016/j.isci.2020.101050 |
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