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A Systematic Review of the Efficacy of Preclinical Models of Lung Cancer Drugs

Background: Preclinical cell models are the mainstay in the early stages of drug development. We sought to explore the preclinical data that differentiated successful from failed therapeutic agents in lung cancer. Methods: One hundred thirty-four failed lung cancer drugs and twenty seven successful...

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Detalles Bibliográficos
Autores principales: Pan, Elizabeth, Bogumil, David, Cortessis, Victoria, Yu, Sherrie, Nieva, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190806/
https://www.ncbi.nlm.nih.gov/pubmed/32391273
http://dx.doi.org/10.3389/fonc.2020.00591