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Minimally Invasive Cell-Free Human Embryo Aneuploidy Testing (miPGT-A) Utilizing Combined Spent Embryo Culture Medium and Blastocoel Fluid –Towards Development of a Clinical Assay

Preimplantation genetic testing for aneuploidies (PGT-A) using trophectoderm (TE) biopsy samples is labour intensive, invasive, and subject to sampling bias. In this study, we report on the efficacy and factors affecting accuracy of a technique we pioneered for minimally invasive preimplantation gen...

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Detalles Bibliográficos
Autores principales: Kuznyetsov, Valeriy, Madjunkova, Svetlana, Abramov, Rina, Antes, Ran, Ibarrientos, Zenon, Motamedi, Gelareh, Zaman, Afsaneh, Kuznyetsova, Iryna, Librach, Clifford L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190856/
https://www.ncbi.nlm.nih.gov/pubmed/32350403
http://dx.doi.org/10.1038/s41598-020-64335-3