Polymorphisms in miRNA binding sites involved in metabolic diseases in mice and humans

Type 2 diabetes and obesity are well-studied metabolic diseases, which are based on genetic and epigenetic alterations in combination with an obesogenic lifestyle. The aim of this study was to test whether SNPs in miRNA-mRNA binding sites that potentially disrupt binding, elevate the expression of m...

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Detalles Bibliográficos
Autores principales: Gottmann, Pascal, Ouni, Meriem, Zellner, Lisa, Jähnert, Markus, Rittig, Kilian, Walther, Dirk, Schürmann, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190857/
https://www.ncbi.nlm.nih.gov/pubmed/32350386
http://dx.doi.org/10.1038/s41598-020-64326-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190857/
https://www.ncbi.nlm.nih.gov/pubmed/32350386
http://dx.doi.org/10.1038/s41598-020-64326-4

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