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Oleoylethanolamide Exhibits GPR119-Dependent Inhibition of Osteoclast Function and GPR119-Independent Promotion of Osteoclast Apoptosis

Oleoylethanolamide (OEA), a bioactive lipid in bone, is known as an endogenous ligand for G protein-coupled receptor 119 (GPR119). Here, we explored the effects of OEA on osteoclast differentiation, function, and survival. While OEA inhibits osteoclast resorptive function by disrupting actin cytoske...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Ju, Lee, Dong-Kyo, Jin, Xian, Che, Xiangguo, Choi, Je-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191045/
https://www.ncbi.nlm.nih.gov/pubmed/32050752
http://dx.doi.org/10.14348/molcells.2020.2260