Structural Basis for the Antibiotic Resistance of Eukaryotic Isoleucyl-tRNA Synthetase

Pathogenic aminoacyl-tRNA synthetases (ARSs) are attractive targets for anti-infective agents because their catalytic active sites are different from those of human ARSs. Mupirocin is a topical antibiotic that specifically inhibits bacterial isoleucyl-tRNA synthetase (IleRS), resulting in a block to...

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Detalles Bibliográficos
Autores principales: Chung, Scisung, Kim, Sulhee, Ryu, Sung Ho, Hwang, Kwang Yeon, Cho, Yunje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191050/
https://www.ncbi.nlm.nih.gov/pubmed/32088946
http://dx.doi.org/10.14348/molcells.2020.2287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191050/
https://www.ncbi.nlm.nih.gov/pubmed/32088946
http://dx.doi.org/10.14348/molcells.2020.2287

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