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Structural Basis for the Antibiotic Resistance of Eukaryotic Isoleucyl-tRNA Synthetase

Pathogenic aminoacyl-tRNA synthetases (ARSs) are attractive targets for anti-infective agents because their catalytic active sites are different from those of human ARSs. Mupirocin is a topical antibiotic that specifically inhibits bacterial isoleucyl-tRNA synthetase (IleRS), resulting in a block to...

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Detalles Bibliográficos
Autores principales:	Chung, Scisung, Kim, Sulhee, Ryu, Sung Ho, Hwang, Kwang Yeon, Cho, Yunje
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191050/ https://www.ncbi.nlm.nih.gov/pubmed/32088946 http://dx.doi.org/10.14348/molcells.2020.2287

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